SLC1A2

Across TCGA cell cohorts, SLC1A2 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC1A2-associated genes across cancer lineages are SPATA19, C20orf85, and BRDT. Each is linked with SLC1A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC1A2-to-partner and partner-to-SLC1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA19 grouped by SLC1A2-low versus SLC1A2-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A2→partner) and Y-score (partner→SLC1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	SPATA19 →	+0.036	+5.000	<.001	.005	3	1
BLOOD_Leukemia	C20orf85 →	+0.033	+4.384	<.001	.006	3	1
BLOOD_Leukemia	BRDT →	+0.172	+4.342	<.001	.002	3	1
BLOOD_Leukemia	UNC45B →	+0.150	+4.408	<.001	.001	3	1
BLOOD_Leukemia	SCN2B →	+0.193	+4.133	<.001	.003	3	1
BLOOD_Leukemia	VWC2L →	+0.016	+4.339	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

SPATA19 by SLC1A2 expression — KIDNEY

Explore this box plot interactively →