SLC18B1

Across TCGA patient cohorts, SLC18B1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,332 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC18B1-associated genes across cancer lineages are SMPDL3B, BTBD6P1, and STRAP. Each is linked with SLC18B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC18B1-to-partner and partner-to-SLC18B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC18B1 versus SMPDL3B in LSCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18B1→partner) and Y-score (partner→SLC18B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMPDL3B →	+1.555	+0.674	<.001	.007	3	2
LSCC	BTBD6P1 →	+0.972	+0.678	<.001	<.001	3	2
LSCC	STRAP →	-0.737	-0.598	.003	.003	3	2
LSCC	MSANTD3 →	-1.017	-0.714	.002	<.001	3	2
OV	SYNGR1 →	-1.076	-0.765	.001	.003	3	1
OV	PRX →	-0.545	-0.596	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,332 associations by consensus.

SLC18B1 vs SMPDL3B — LSCC

Explore this scatter interactively →