SLC18A2

Across TCGA patient cohorts, SLC18A2 mutation is significantly associated with the RNA expression of many other genes, with 2,905 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC18A2-associated genes across cancer lineages are RN7SKP245, STARD4, and DDIT4. Each is linked with SLC18A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC18A2-to-partner and partner-to-SLC18A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP245 grouped by SLC18A2-low versus SLC18A2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A2→partner) and Y-score (partner→SLC18A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SKP245 →	+0.106	+4.812	<.001	<.001	3	3
SKCM	STARD4 →	+0.856	+2.603	.004	.005	3	3
UCEC	DDIT4 →	+1.036	+2.459	<.001	<.001	3	3
UCEC	TRABD →	+0.377	+4.119	.009	<.001	3	3
UCEC	TYMS →	+0.759	+3.095	.001	<.001	3	3
UCEC	RCC1 →	+0.391	+2.595	.009	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,905 associations by consensus.

RN7SKP245 by SLC18A2 expression — CESC

Explore this box plot interactively →