SLC18A1

Across TCGA cell cohorts, SLC18A1 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC18A1-associated genes across cancer lineages are ODF1, MSGN1, and OR14K1. Each is linked with SLC18A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC18A1-to-partner and partner-to-SLC18A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ODF1 grouped by SLC18A1-low versus SLC18A1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A1→partner) and Y-score (partner→SLC18A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ODF1 →	+0.016	+4.437	<.001	.004	3	2
LARGE_INTESTINE	MSGN1 →	+0.080	+3.760	<.001	<.001	3	1
LARGE_INTESTINE	OR14K1 →	+0.058	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TDRD10 →	+0.053	+2.878	.009	.009	3	1
LARGE_INTESTINE	TAFA1 →	+0.241	+4.009	.001	<.001	3	1
LARGE_INTESTINE	PNMA3 →	+0.164	+3.781	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

ODF1 by SLC18A1 expression — SKIN

Explore this box plot interactively →