SLC17A9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC17A9 mutation is significantly associated with the RNA expression of many other genes, with 1,004 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC17A9-associated genes across cancer lineages are PYY3, MIR652, and DUX4L17. Each is linked with SLC17A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC17A9-to-partner and partner-to-SLC17A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PYY3 grouped by SLC17A9-low versus SLC17A9-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A9→partner) and Y-score (partner→SLC17A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPYY3 →+0.205+5.142<.001.00233
CESCMIR652 →+0.298+4.669<.001.00732
SKCMDUX4L17 →+0.009+4.025<.001.00732
SKCMLINC02841 →+0.021+4.769<.001.00232
COADLINC02349 →+0.118+4.251.001.00832
HNSCRNA5SP197 →+0.538+4.372<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,004 associations by consensus.

PYY3 by SLC17A9 expression — COAD

Box plot of PYY3 in SLC17A9-low vs SLC17A9-high samples in COAD.

Explore this box plot interactively →

Exploration