SLC17A9

Across TCGA pan-cancer cohorts, SLC17A9 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated SLC17A9 data layer compared with 7 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SLC17A9 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC17A9 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

KIRC, UVM, and HNSC are the cancer types where SLC17A9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.509	0.722	<.001	128	view →
UVM	DFS	Median	All	0.407	0.783	<.001	108	view →
HNSC	DFS	Median	IV	0.735	0.545	<.001	82	view →
ACC	OS	Median	All	0.668	0.970	<.001	67	view →
LUAD	OS	Tertile	II,III,IV	0.647	0.441	.002	64	view →
LGG	DFS	Median	All	0.252	0.488	<.001	53	view →
DLBC	DFS	Median	All	0.629	1.000	.017	27	view →
CHOL	DFS	Median	II,III,IV	0.121	0.626	.002	24	view →
GBM	DFS	Median	All	0.163	0.238	.008	21	view →
THYM	DFS	Tertile	II,III,IV	0.639	1.000	.005	19	view →
THCA	DFS	Quartile	II,III,IV	1.000	0.522	.005	18	view →
SKCM	OS	Quartile	III,IV	0.614	0.278	.003	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

SLC17A9–KIRC (DFS)

Open the KIRC breakdown →