SLC17A9

Across TCGA patient cohorts, SLC17A9 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC17A9-associated genes across cancer lineages are p27_pT198, PCNA, and PRDX1. Each is linked with SLC17A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC17A9-to-partner and partner-to-SLC17A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p27_pT198 grouped by SLC17A9-low versus SLC17A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A9→partner) and Y-score (partner→SLC17A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT198 →	+0.114	+1.584	.006	.036	3	2
UCEC	PCNA →	+0.220	+2.999	.009	.035	3	2
UCEC	PRDX1 →	+0.178	+2.000	.027	.030	3	2
UCEC	ATM →	-0.359	-2.584	.043	.010	3	2
UCEC	c-Kit →	-0.230	-2.308	.012	.033	3	2
UCEC	14-3-3_beta →	-0.096	-2.295	.014	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

p27_pT198 by SLC17A9 expression — UCEC

Explore this box plot interactively →