SLC17A9

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC17A9 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC17A9-associated genes across cancer lineages are CYP4A11, OR13D1, and OR2AJ1. Each is linked with SLC17A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC17A9-to-partner and partner-to-SLC17A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYP4A11 grouped by SLC17A9-low versus SLC17A9-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A9→partner) and Y-score (partner→SLC17A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaCYP4A11 →+0.006+4.807<.001.00632
SOFT_TISSUEOR13D1 →+0.025+4.977<.001.00232
BLOOD_MyelomaOR2AJ1 →+0.013+4.807<.001.00631
BLOOD_MyelomaOR4D2 →+0.013+4.807<.001.00631
SOFT_TISSUEH2BC1 →+0.325+4.977<.001.00231
SOFT_TISSUEH2AC1 →+0.145+4.977<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

CYP4A11 by SLC17A9 expression — BLOOD_Myeloma

Box plot of CYP4A11 in SLC17A9-low vs SLC17A9-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration