SLC17A7

Across TCGA cell cohorts, SLC17A7 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC17A7-associated genes across cancer lineages are CFAP97D2, OR5P3, and MYOD1. Each is linked with SLC17A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC17A7-to-partner and partner-to-SLC17A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFAP97D2 grouped by SLC17A7-low versus SLC17A7-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A7→partner) and Y-score (partner→SLC17A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CFAP97D2 →	+0.043	+5.087	<.001	.004	3	2
BLOOD_Leukemia	OR5P3 →	+0.081	+4.786	<.001	<.001	3	2
LARGE_INTESTINE	MYOD1 →	+0.011	+2.777	<.001	.004	3	2
LUNG_NSCLC_LUSC	CLRN1 →	+0.013	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	TMCO5A →	+0.060	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	OR1L3 →	+0.060	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

CFAP97D2 by SLC17A7 expression — URINARY_TRACT

Explore this box plot interactively →