SLC17A2

Across TCGA cell cohorts, SLC17A2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC17A2-associated genes across cancer lineages are PIGY, GGTLC2, and LCE2B. Each is linked with SLC17A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC17A2-to-partner and partner-to-SLC17A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PIGY grouped by SLC17A2-low versus SLC17A2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A2→partner) and Y-score (partner→SLC17A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	PIGY →	+2.475	+3.584	<.001	.009	3	2
SKIN	GGTLC2 →	+0.032	+4.273	<.001	.006	3	2
SOFT_TISSUE	LCE2B →	+0.030	+4.977	<.001	.002	3	1
SOFT_TISSUE	KRT35 →	+0.224	+4.222	<.001	.007	3	1
SOFT_TISSUE	IFNA14 →	+0.024	+4.369	<.001	.008	3	1
URINARY_TRACT	SERPINI2 →	+0.081	+3.584	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

PIGY by SLC17A2 expression — URINARY_TRACT

Explore this box plot interactively →