SLC17A2

Across TCGA cell cohorts, SLC17A2 mutation is significantly associated with the mutation status of many other genes, with 3,380 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC17A2-associated genes across cancer lineages are ASXL3, PCARE, and NWD1. Each is linked with SLC17A2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC17A2-to-partner and partner-to-SLC17A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASXL3 grouped by SLC17A2-low versus SLC17A2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A2→partner) and Y-score (partner→SLC17A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ASXL3 →	+2.985	+3.562	.008	.008	1	4
SKIN	PCARE →	+2.807	+4.247	.007	.007	1	4
BLOOD_Lymphoma	NWD1 →	+4.316	+3.832	.002	.002	1	4
CNS	DAAM2 →	+4.459	+5.277	.005	.005	1	4
UPPER_AERODIGESTIVE_TRACT	ANO1 →	+5.392	+5.392	.004	.004	1	4
LARGE_INTESTINE	NUP210L →	+2.222	+2.925	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,380 associations by consensus.

ASXL3 by SLC17A2 expression — SOFT_TISSUE

Explore this box plot interactively →