SLC17A1

Across TCGA patient cohorts, SLC17A1 mutation is significantly associated with the RNA expression of many other genes, with 4,748 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC17A1-associated genes across cancer lineages are RN7SL837P, RNU6-1213P, and RNA5SP322. Each is linked with SLC17A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC17A1-to-partner and partner-to-SLC17A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL837P grouped by SLC17A1-low versus SLC17A1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A1→partner) and Y-score (partner→SLC17A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL837P →	+0.033	+3.330	<.001	.003	3	3
UCEC	RNU6-1213P →	+0.166	+3.292	<.001	<.001	3	3
COAD	RNA5SP322 →	+0.413	+4.399	<.001	.006	3	2
COAD	RNU6-1323P →	+0.309	+4.821	<.001	.003	3	2
COAD	H3P27 →	+0.091	+4.399	<.001	.006	3	2
COAD	RFC3P1 →	+0.069	+4.821	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,748 associations by consensus.

RN7SL837P by SLC17A1 expression — SKCM

Explore this box plot interactively →