SLC16A9

Across TCGA patient cohorts, SLC16A9 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A9-associated genes across cancer lineages are 14-3-3_beta, Tuberin, and Notch1. Each is linked with SLC16A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A9-to-partner and partner-to-SLC16A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by SLC16A9-low versus SLC16A9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A9→partner) and Y-score (partner→SLC16A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	14-3-3_beta →	-0.113	-3.000	.029	.034	3	2
UCEC	Tuberin →	+0.308	+1.906	.004	.016	3	2
UCEC	Notch1 →	+0.184	+3.331	.001	.005	3	2
UCEC	Rab25 →	-0.390	-2.415	.003	.003	3	2
UCEC	Di-Ras3 →	-0.172	-3.446	.004	.005	3	2
SKCM	ER-alpha →	-0.147	-1.840	.049	.047	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

14-3-3_beta by SLC16A9 expression — SKCM

Explore this box plot interactively →