SLC16A8

Across TCGA cell cohorts, SLC16A8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,786 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC16A8-associated GO terms across cancer lineages are Positive regulation of striated muscle contraction, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with SLC16A8 in more than 13 cancer types. Because this analysis shows association rather than direction, both SLC16A8-to-partner and partner-to-SLC16A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of striated muscle contraction grouped by SLC16A8-low versus SLC16A8-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A8→partner) and Y-score (partner→SLC16A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of striated muscle contraction →	-0.283	-1.391	.004	.004	3	14
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.152	+1.502	.001	.001	3	14
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.153	+1.502	<.001	.001	3	14
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.138	+1.462	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	+0.079	+0.542	<.001	<.001	2	14
URINARY_TRACT	Regulation of TORC1 signaling →	+0.063	+0.893	.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,786 associations by consensus.

Positive regulation of striated muscle contraction by SLC16A8 expression — OESOPHAGUS

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