SLC16A8

Across TCGA cell cohorts, SLC16A8 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC16A8-associated genes across cancer lineages are OR4M2, SPHKAP, and CST5. Each is linked with SLC16A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A8-to-partner and partner-to-SLC16A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4M2 grouped by SLC16A8-low versus SLC16A8-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A8→partner) and Y-score (partner→SLC16A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR4M2 →	+0.156	+4.977	<.001	.007	3	1
LARGE_INTESTINE	SPHKAP →	+0.006	+5.415	.007	.004	3	1
BLOOD_Leukemia	CST5 →	+0.490	+4.551	<.001	.004	3	1
BLOOD_Leukemia	GDF5-AS1 →	+0.029	+4.481	<.001	.004	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR4M2 by SLC16A8 expression — SKIN

Explore this box plot interactively →