SLC16A6

Across TCGA patient cohorts, SLC16A6 mutation is significantly associated with the RNA expression of many other genes, with 1,493 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A6-associated genes across cancer lineages are RNU6-552P, RN7SL519P, and BCAR1P2. Each is linked with SLC16A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A6-to-partner and partner-to-SLC16A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-552P grouped by SLC16A6-low versus SLC16A6-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A6→partner) and Y-score (partner→SLC16A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-552P →	+0.488	+5.106	<.001	.008	3	2
PRAD	RN7SL519P →	+0.221	+5.807	<.001	.003	3	2
PRAD	BCAR1P2 →	+0.097	+5.166	<.001	.007	3	2
HNSC	OR1A1 →	+0.061	+5.124	<.001	.008	3	2
HNSC	RNU6-707P →	+0.432	+6.339	<.001	.001	3	2
SKCM	CYCSP26 →	+0.166	+6.485	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,493 associations by consensus.

RNU6-552P by SLC16A6 expression — BLCA

Explore this box plot interactively →