SLC16A5

Across TCGA patient cohorts, SLC16A5 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A5-associated genes across cancer lineages are Fibronectin, FoxM1, and FOXO3a. Each is linked with SLC16A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A5-to-partner and partner-to-SLC16A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibronectin grouped by SLC16A5-low versus SLC16A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A5→partner) and Y-score (partner→SLC16A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Fibronectin →	-0.332	-3.160	.030	.019	3	1
UCEC	FoxM1 →	+0.291	+2.584	.016	.011	3	1
UCEC	FOXO3a →	+0.116	+1.887	.013	.031	3	1
UCEC	AMPK_pT172 →	+0.419	+2.598	.028	.006	3	1
UCEC	Rictor_pT1135 →	-0.131	-3.169	.005	.018	3	1
UCEC	Smac →	+0.240	+3.169	.048	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Fibronectin by SLC16A5 expression — UCEC

Explore this box plot interactively →