SLC16A5

Across TCGA cell cohorts, SLC16A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,159 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC16A5-associated GO terms across cancer lineages are Death-inducing signaling complex assembly, Xenophagy, and Negative regulation of response to type II interferon. Each is linked with SLC16A5 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC16A5-to-partner and partner-to-SLC16A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Death-inducing signaling complex assembly grouped by SLC16A5-low versus SLC16A5-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A5→partner) and Y-score (partner→SLC16A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Death-inducing signaling complex assembly →	+0.114	+1.702	.002	.001	3	9
LUNG_NSCLC_LUSC	Xenophagy →	+0.167	+2.085	.005	.005	3	9
OESOPHAGUS	Negative regulation of response to type II interferon →	+0.191	+2.789	<.001	<.001	3	9
OESOPHAGUS	Negative regulation of type II interferon-mediated signaling pathway →	+0.191	+2.789	<.001	<.001	3	9
PANCREAS	Nuclear receptor-mediated signaling pathway →	+0.056	+1.559	.001	.004	3	9
STOMACH	Regulation of protein localization to plasma membrane →	+0.109	+2.582	.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,159 associations by consensus.

Death-inducing signaling complex assembly by SLC16A5 expression — BREAST

Explore this box plot interactively →