SLC16A3

Across TCGA cell cohorts, SLC16A3 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC16A3-associated genes across cancer lineages are ASB11, LINGO2, and MAGEB4. Each is linked with SLC16A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A3-to-partner and partner-to-SLC16A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB11 grouped by SLC16A3-low versus SLC16A3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A3→partner) and Y-score (partner→SLC16A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ASB11 →	+0.082	+3.007	<.001	.007	3	1
BLOOD_Leukemia	LINGO2 →	+0.622	+3.793	<.001	.004	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+5.415	.009	.004	3	1
SKIN	KRTAP5-10 →	+0.045	+3.242	<.001	.003	3	1
SKIN	HNRNPCL3 →	+0.038	+3.376	<.001	.002	3	1
BREAST	OR2G6 →	+0.016	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ASB11 by SLC16A3 expression — BLOOD_Leukemia

Explore this box plot interactively →