SLC16A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC16A2 mutation is significantly associated with the RNA expression of many other genes, with 4,084 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A2-associated genes across cancer lineages are RNA5SP457, LINC02093, and MIR548AL. Each is linked with SLC16A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A2-to-partner and partner-to-SLC16A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP457 grouped by SLC16A2-low versus SLC16A2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A2→partner) and Y-score (partner→SLC16A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNA5SP457 →+0.334+3.758<.001.00832
BLCALINC02093 →+0.155+3.926<.001.00532
CESCMIR548AL →+0.190+4.757<.001.00432
CESCSSX4 →+0.054+4.559<.001.00632
CESCOR5D17P →+0.025+5.579<.001.00132
CESCKRTAP8-2P →+0.112+4.757<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,084 associations by consensus.

RNA5SP457 by SLC16A2 expression — BLCA

Box plot of RNA5SP457 in SLC16A2-low vs SLC16A2-high samples in BLCA.

Explore this box plot interactively →

Exploration