SLC16A12

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC16A12 mutation is significantly associated with the RNA expression of many other genes, with 3,001 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A12-associated genes across cancer lineages are RN7SL314P, PELO, and FARP1. Each is linked with SLC16A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A12-to-partner and partner-to-SLC16A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL314P grouped by SLC16A12-low versus SLC16A12-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A12→partner) and Y-score (partner→SLC16A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL314P →+0.430+7.154<.001<.00132
UCECPELO →+0.468+2.950<.001<.00132
SKCMFARP1 →+0.653+3.350.008.00532
UCECRAD17 →+0.437+2.070.001.00132
UCECCENPH →+0.548+2.081.001.00132
UCECTOMM70 →+0.392+3.606.003.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,001 associations by consensus.

RN7SL314P by SLC16A12 expression — CESC

Box plot of RN7SL314P in SLC16A12-low vs SLC16A12-high samples in CESC.

Explore this box plot interactively →

Exploration