SLC16A12

Across TCGA cell cohorts, SLC16A12 mutation is significantly associated with the RNA expression of many other genes, with 278 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC16A12-associated genes across cancer lineages are MIOX, GNPNAT1, and DNASE2. Each is linked with SLC16A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A12-to-partner and partner-to-SLC16A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIOX grouped by SLC16A12-low versus SLC16A12-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A12→partner) and Y-score (partner→SLC16A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MIOX →	+0.343	+3.502	<.001	.001	3	1
LARGE_INTESTINE	GNPNAT1 →	+0.632	+2.451	<.001	.009	3	1
LARGE_INTESTINE	DNASE2 →	+0.911	+3.502	.001	.001	3	1
LARGE_INTESTINE	DPH1 →	+0.646	+3.321	.006	.003	3	1
LARGE_INTESTINE	KLF3 →	+0.778	+3.502	<.001	.001	3	1
LARGE_INTESTINE	FAM149A →	+1.448	+3.252	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 278 associations by consensus.

MIOX by SLC16A12 expression — LARGE_INTESTINE

Explore this box plot interactively →