SLC16A11

Across TCGA cell cohorts, SLC16A11 mutation is significantly associated with the mutation status of many other genes, with 2,045 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC16A11-associated genes across cancer lineages are MTA1, PPARGC1B, and AGAP1. Each is linked with SLC16A11 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC16A11-to-partner and partner-to-SLC16A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTA1 grouped by SLC16A11-low versus SLC16A11-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A11→partner) and Y-score (partner→SLC16A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MTA1 →	+4.415	+4.977	.007	.007	1	3
OVARY	PPARGC1B →	+5.415	+5.415	.004	.004	1	3
OVARY	AGAP1 →	+4.415	+4.977	.007	.007	1	3
LARGE_INTESTINE	IGDCC4 →	+2.865	+4.217	.007	.007	1	3
OVARY	KNG1 →	+5.415	+5.415	.004	.004	1	3
BLOOD_Leukemia	GBE1 →	+5.321	+5.894	.002	.002	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,045 associations by consensus.

MTA1 by SLC16A11 expression — OVARY

Explore this box plot interactively →