SLC15A3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC15A3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,195 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC15A3-associated genes across cancer lineages are LAIR1, CD86, and SIGLEC9. Each is linked with SLC15A3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC15A3-to-partner and partner-to-SLC15A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC15A3 versus LAIR1 in HNSC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC15A3→partner) and Y-score (partner→SLC15A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCLAIR1 →+1.975+0.759<.001.00127
COADCD86 →+2.419+0.907<.001<.00135
COADSIGLEC9 →+1.439+0.836<.001.00435
COADCCR1 →+1.333+0.621<.001<.00135
COADCYBB →+2.308+0.907<.001<.00135
COADMSR1 →+2.097+0.802.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,195 associations by consensus.

SLC15A3 vs LAIR1 — HNSC

Per-sample scatter of SLC15A3 vs LAIR1 in HNSC (Pearson r = 0.64).

Explore this scatter interactively →

Exploration