SLC15A2

Across TCGA cell cohorts, SLC15A2 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC15A2-associated genes across cancer lineages are IFNA2, DAOA, and C1QB. Each is linked with SLC15A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC15A2-to-partner and partner-to-SLC15A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA2 grouped by SLC15A2-low versus SLC15A2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC15A2→partner) and Y-score (partner→SLC15A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IFNA2 →	+0.339	+4.121	<.001	<.001	3	2
LUNG_NSCLC_LUAD	DAOA →	+0.014	+4.681	<.001	.003	3	2
PANCREAS	C1QB →	+0.026	+5.614	<.001	.002	3	1
PANCREAS	GLT6D1 →	+0.006	+5.614	<.001	.002	3	1
BLOOD_Leukemia	F9 →	+0.011	+3.969	<.001	.009	3	1
BLOOD_Leukemia	LUZP4 →	+0.322	+3.475	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

IFNA2 by SLC15A2 expression — BLOOD_Leukemia

Explore this box plot interactively →