SLC15A2

Across TCGA pan-cancer cohorts, SLC15A2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated SLC15A2 data layer compared with 11 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC15A2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC15A2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

LUAD, SKCM, and LGG are the cancer types where SLC15A2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.732	0.601	<.001	51	view →
SKCM	OS	Quartile	All	0.398	0.229	<.001	43	view →
LGG	OS	Median	All	0.933	0.855	<.001	42	view →
STAD	DFS	Quartile	II,III,IV	0.394	0.659	.004	39	view →
READ	DFS	Quartile	II,III,IV	0.941	0.457	.009	28	view →
HNSC	DFS	Median	IV	0.749	0.588	.009	26	view →
CESC	OS	Quartile	All	0.951	0.824	.002	18	view →
LIHC	OS	Tertile	All	0.609	0.774	.003	16	view →
BRCA	OS	Quartile	III,IV	0.825	0.945	.005	14	view →
SARC	OS	Median	All	0.822	0.637	.003	9	view →
BLCA	OS	Quartile	All	0.482	0.720	.018	9	view →
UCS	DFS	Median	III,IV	0.570	0.269	.010	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

SLC15A2–LUAD (DFS)

Open the LUAD breakdown →