SLC13A5

Across TCGA patient cohorts, SLC13A5 mutation is significantly associated with the RNA expression of many other genes, with 3,324 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC13A5-associated genes across cancer lineages are PSAT1P4, DLAT, and NKAPD1. Each is linked with SLC13A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC13A5-to-partner and partner-to-SLC13A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSAT1P4 grouped by SLC13A5-low versus SLC13A5-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A5→partner) and Y-score (partner→SLC13A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	PSAT1P4 →	+0.123	+4.503	<.001	.005	3	2
UCEC	DLAT →	+0.592	+2.058	<.001	<.001	3	2
UCEC	NKAPD1 →	+0.421	+3.917	<.001	<.001	3	2
UCEC	FAM177A1 →	+0.446	+2.765	<.001	<.001	3	2
UCEC	VTI1A →	+0.298	+2.080	.004	<.001	3	2
UCEC	HOMER1 →	+0.718	+2.378	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,324 associations by consensus.

PSAT1P4 by SLC13A5 expression — CESC

Explore this box plot interactively →