SLC13A3

Across TCGA patient cohorts, SLC13A3 mutation is significantly associated with the RNA expression of many other genes, with 2,648 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC13A3-associated genes across cancer lineages are HNRNPH3P1, RNU6-238P, and TTTY15. Each is linked with SLC13A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC13A3-to-partner and partner-to-SLC13A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPH3P1 grouped by SLC13A3-low versus SLC13A3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A3→partner) and Y-score (partner→SLC13A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HNRNPH3P1 →	+0.041	+4.505	<.001	.006	3	2
READ	RNU6-238P →	+0.308	+4.421	<.001	.001	3	2
SKCM	TTTY15 →	+0.738	+1.743	.005	.004	3	2
COAD	KIR3DL2 →	+0.338	+3.291	<.001	<.001	3	2
UCEC	CORT →	+0.420	+2.111	<.001	.003	3	2
COAD	SNRPCP20 →	+0.306	+2.760	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,648 associations by consensus.

HNRNPH3P1 by SLC13A3 expression — BRCA

Explore this box plot interactively →