SLC13A2

Across TCGA patient cohorts, SLC13A2 mutation is significantly associated with the RNA expression of many other genes, with 4,270 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC13A2-associated genes across cancer lineages are CCL18, BUB1B, and DONSON. Each is linked with SLC13A2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC13A2-to-partner and partner-to-SLC13A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL18 grouped by SLC13A2-low versus SLC13A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A2→partner) and Y-score (partner→SLC13A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCL18 →	+1.191	+2.584	<.001	<.001	3	4
UCEC	BUB1B →	+0.706	+2.928	<.001	<.001	3	3
UCEC	DONSON →	+0.508	+4.032	<.001	<.001	3	3
UCEC	CHAF1B →	+0.611	+2.273	<.001	<.001	3	3
UCEC	PKN3 →	+0.825	+2.964	<.001	<.001	3	3
UCEC	SFXN1 →	+0.503	+3.269	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,270 associations by consensus.

CCL18 by SLC13A2 expression — UCEC

Explore this box plot interactively →