SLC13A1

Across TCGA patient cohorts, SLC13A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,620 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SLC13A1-associated GO terms across cancer lineages are Regulation of macroautophagy, Protein targeting to membrane, and Positive regulation of double-strand break repair. Each is linked with SLC13A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC13A1-to-partner and partner-to-SLC13A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by SLC13A1-low versus SLC13A1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A1→partner) and Y-score (partner→SLC13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of macroautophagy →	+0.101	+0.117	<.001	<.001	3	9
STAD	Protein targeting to membrane →	+0.058	+0.117	<.001	<.001	3	9
SCLC	Positive regulation of double-strand break repair →	+0.100	+0.357	<.001	<.001	3	8
STAD	Vesicle-mediated transport to the plasma membrane →	+0.061	+0.136	<.001	<.001	3	8
STAD	Carbohydrate catabolic process →	+0.054	+0.123	<.001	<.001	3	8
STAD	Stress-activated protein kinase signaling cascade →	+0.090	+0.120	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,620 associations by consensus.

Regulation of macroautophagy by SLC13A1 expression — STAD

Explore this box plot interactively →