SLC13A1

Across TCGA pan-cancer cohorts, SLC13A1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SLC13A1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where SLC13A1 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC13A1 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, COAD, and KIRP are the cancer types where SLC13A1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC13A1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	II,III,IV	−4.151	<.001	10	view →
COAD	All	All	−0.445	.004	10	view →
KIRP	All	III,IV	−2.889	<.001	5	view →
CHOL	Female	All	+2.559	.001	3	view →
KIRC	Male	III,IV	−1.328	.037	2	view →
READ	All	All	−0.182	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

SLC13A1–KICH

Open the KICH breakdown →