SLC13A1

Across TCGA patient cohorts, SLC13A1 mutation is significantly associated with the RNA expression of many other genes, with 4,996 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC13A1-associated genes across cancer lineages are MPV17L2, PTH1R, and HDGFL2. Each is linked with SLC13A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC13A1-to-partner and partner-to-SLC13A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPV17L2 grouped by SLC13A1-low versus SLC13A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A1→partner) and Y-score (partner→SLC13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MPV17L2 →	+0.339	+2.595	<.001	<.001	3	3
UCEC	PTH1R →	-0.606	-1.376	.001	.001	3	3
UCEC	HDGFL2 →	+0.404	+1.710	<.001	<.001	3	3
UCEC	SIRT6 →	+0.390	+1.898	<.001	<.001	3	3
KIRP	PSPC1P2 →	+0.221	+5.376	<.001	.005	3	2
BRCA	GCSHP1 →	+0.097	+6.016	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,996 associations by consensus.

MPV17L2 by SLC13A1 expression — UCEC

Explore this box plot interactively →