SLC13A1

Across TCGA cell cohorts, SLC13A1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC13A1-associated genes across cancer lineages are TPPP2, PIP, and NCBP2L. Each is linked with SLC13A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC13A1-to-partner and partner-to-SLC13A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TPPP2 grouped by SLC13A1-low versus SLC13A1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A1→partner) and Y-score (partner→SLC13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TPPP2 →	+0.043	+3.217	<.001	.006	3	2
BLOOD_Lymphoma	PIP →	+0.101	+3.843	.004	.007	3	1
BLOOD_Lymphoma	NCBP2L →	+0.011	+4.058	.002	.009	3	1
BLOOD_Lymphoma	C18orf63 →	+0.009	+4.452	<.001	.001	3	1
BLOOD_Lymphoma	IQCJ →	+0.510	+3.843	<.001	.007	3	1
LUNG_SCLC	TAAR5 →	+0.020	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

TPPP2 by SLC13A1 expression — SKIN

Explore this box plot interactively →