SLC12A9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC12A9 mutation is significantly associated with the RNA expression of many other genes, with 4,181 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC12A9-associated genes across cancer lineages are RPL32P23, RN7SL447P, and SAP30. Each is linked with SLC12A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC12A9-to-partner and partner-to-SLC12A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL32P23 grouped by SLC12A9-low versus SLC12A9-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A9→partner) and Y-score (partner→SLC12A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READRPL32P23 →+0.289+6.257<.001.00133
UCECRN7SL447P →+0.183+2.217<.001<.00133
UCECSAP30 →+0.457+1.436.003.00633
LUADFTSJ3 →+0.490+3.584.003.00333
LUADLINC01620 →+0.056+2.268.001.00633
UCECTAF9 →+0.611+4.269<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,181 associations by consensus.

RPL32P23 by SLC12A9 expression — READ

Box plot of RPL32P23 in SLC12A9-low vs SLC12A9-high samples in READ.

Explore this box plot interactively →

Exploration