SLC12A9

Across TCGA patient cohorts, SLC12A9 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC12A9-associated genes across cancer lineages are INPP4B, PCNA, and ATM. Each is linked with SLC12A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC12A9-to-partner and partner-to-SLC12A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by SLC12A9-low versus SLC12A9-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A9→partner) and Y-score (partner→SLC12A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.486	-2.991	.012	.036	3	3
UCEC	PCNA →	+0.259	+2.169	<.001	.003	3	3
UCEC	ATM →	-0.604	-2.137	<.001	.001	3	3
LUSC	MSH2 →	+0.304	+1.883	.019	.031	3	2
LUSC	Rb_pS807_S811 →	+0.450	+3.000	.014	.035	3	2
UCEC	EGFR_pY1068 →	-0.181	-1.247	.034	.045	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

INPP4B by SLC12A9 expression — COAD

Explore this box plot interactively →