SLC12A9

Across TCGA cell cohorts, SLC12A9 mutation is significantly associated with the mutation status of many other genes, with 3,111 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC12A9-associated genes across cancer lineages are AGL, PREX2, and ZNF628. Each is linked with SLC12A9 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC12A9-to-partner and partner-to-SLC12A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AGL grouped by SLC12A9-low versus SLC12A9-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A9→partner) and Y-score (partner→SLC12A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AGL →	+3.584	+4.922	.001	.001	1	5
BLOOD_Leukemia	PREX2 →	+3.313	+3.430	.005	.005	1	5
CNS	ZNF628 →	+5.862	+5.199	<.001	<.001	1	4
SKIN	ASH1L →	+2.830	+3.548	.009	.009	1	4
CNS	RHBDF2 →	+5.277	+4.459	.005	.005	1	4
SKIN	FLT4 →	+3.638	+4.117	.002	.002	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,111 associations by consensus.

AGL by SLC12A9 expression — BLOOD_Lymphoma

Explore this box plot interactively →