Across TCGA patient cohorts, SLC12A8 protein abundance is significantly associated with the RNA expression of many other genes, with 4,312 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC12A8-associated genes across cancer lineages are HAAO, COPB2, and PPP4R3A. Each is linked with SLC12A8 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC12A8-to-partner and partner-to-SLC12A8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A8→partner) and Y-score (partner→SLC12A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HAAO →	-1.756	-1.107	<.001	<.001	3	3
LSCC	COPB2 →	+0.471	+0.579	<.001	<.001	3	3
CCRCC	PPP4R3A →	-0.510	-0.747	<.001	.002	3	2
CCRCC	PLCB4 →	+2.270	+0.757	<.001	.001	3	2
CCRCC	TBL1X →	-1.138	-0.750	.002	.001	3	2
CCRCC	ARHGEF7 →	-1.020	-1.000	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,312 associations by consensus.

Exploration

SLC12A8 survival (RNA) · tumor vs normal (RNA) · all SLC12A8 data types