SLC12A4

Across TCGA cell cohorts, SLC12A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,441 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC12A4-associated GO terms across cancer lineages are Endosomal transport, Macroautophagy, and Protein stabilization. Each is linked with SLC12A4 in more than 16 cancer types. Because this analysis shows association rather than direction, both SLC12A4-to-partner and partner-to-SLC12A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by SLC12A4-low versus SLC12A4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A4→partner) and Y-score (partner→SLC12A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endosomal transport →	+0.081	+1.779	<.001	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.057	+1.218	<.001	<.001	3	15
OESOPHAGUS	Protein stabilization →	+0.068	+1.587	.009	.008	3	15
UPPER_AERODIGESTIVE_TRACT	Vacuole organization →	+0.047	+1.248	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Negative regulation of organelle assembly →	+0.095	+2.095	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular protein transport →	+0.105	+1.882	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,441 associations by consensus.

Endosomal transport by SLC12A4 expression — BONE

Explore this box plot interactively →