SLC12A2

Across TCGA patient cohorts, SLC12A2 mutation is significantly associated with the RNA expression of many other genes, with 4,358 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC12A2-associated genes across cancer lineages are FARP1-AS1, ENTPD6, and RN7SL38P. Each is linked with SLC12A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC12A2-to-partner and partner-to-SLC12A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FARP1-AS1 grouped by SLC12A2-low versus SLC12A2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A2→partner) and Y-score (partner→SLC12A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FARP1-AS1 →	+0.567	+3.210	.005	.009	3	3
LUAD	ENTPD6 →	+0.623	+3.632	<.001	.001	3	3
LUAD	RN7SL38P →	+0.248	+2.874	.006	.004	3	3
UCEC	PPP6R1 →	+0.308	+1.269	.005	.003	3	3
UCEC	LIG1 →	+0.376	+1.780	<.001	.003	3	3
UCEC	FOXRED1 →	+0.278	+2.043	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,358 associations by consensus.

FARP1-AS1 by SLC12A2 expression — COAD

Explore this box plot interactively →