SLC12A2

Across TCGA cell cohorts, SLC12A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,972 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC12A2-associated GO terms across cancer lineages are Transepithelial ammonium transport, Transepithelial chloride transport, and Ammonium transmembrane transport. Each is linked with SLC12A2 in more than 19 cancer types. Because this analysis shows association rather than direction, both SLC12A2-to-partner and partner-to-SLC12A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transepithelial ammonium transport grouped by SLC12A2-low versus SLC12A2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A2→partner) and Y-score (partner→SLC12A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Transepithelial ammonium transport →	+1.685	+1.855	<.001	<.001	2	20
BREAST	Transepithelial chloride transport →	+0.134	+1.781	.005	<.001	3	11
PANCREAS	Ammonium transmembrane transport →	+1.532	+1.970	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid metabolic process →	+0.043	+1.502	<.001	<.001	3	10
LUNG_SCLC	T cell chemotaxis →	+1.187	+1.084	.001	.009	3	10
PANCREAS	Response to potassium ion →	+0.192	+1.866	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,972 associations by consensus.

Transepithelial ammonium transport by SLC12A2 expression — URINARY_TRACT

Explore this box plot interactively →