SLC11A2

Across TCGA patient cohorts, SLC11A2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,699 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC11A2-associated genes across cancer lineages are GMFG, SLCO2B1, and ATP6V1C2. Each is linked with SLC11A2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC11A2-to-partner and partner-to-SLC11A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC11A2 versus GMFG in BRCA, with a Pearson correlation of -0.22.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC11A2→partner) and Y-score (partner→SLC11A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GMFG →	-0.542	-0.449	.003	.002	3	4
LSCC	SLCO2B1 →	-0.753	-0.361	<.001	<.001	3	4
UCEC	ATP6V1C2 →	+0.881	+0.432	.002	<.001	3	4
OV	STARD8 →	-0.954	-0.989	.004	.008	3	4
CCRCC	ZNF366 →	-0.641	-0.356	.002	.003	3	4
HNSC	APOL3 →	-1.093	-0.364	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,699 associations by consensus.

SLC11A2 vs GMFG — BRCA

Explore this scatter interactively →