SLC11A1

Across TCGA patient cohorts, SLC11A1 mutation is significantly associated with the RNA expression of many other genes, with 1,667 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC11A1-associated genes across cancer lineages are RN7SL248P, OR51T1, and PEX12P1. Each is linked with SLC11A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC11A1-to-partner and partner-to-SLC11A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by SLC11A1-low versus SLC11A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC11A1→partner) and Y-score (partner→SLC11A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.051	+2.847	<.001	.008	3	3
OV	OR51T1 →	+0.090	+5.572	<.001	.004	3	2
OV	PEX12P1 →	+0.040	+5.297	<.001	.006	3	2
OV	RN7SL332P →	+0.144	+5.297	<.001	.006	3	2
LUAD	RNU6-679P →	+0.689	+5.481	.001	.005	3	2
UCEC	MIR3661 →	+0.480	+1.604	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,667 associations by consensus.

RN7SL248P by SLC11A1 expression — UCEC

Explore this box plot interactively →