SLC10A6

Across TCGA patient cohorts, SLC10A6 mutation is significantly associated with the RNA expression of many other genes, with 1,085 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC10A6-associated genes across cancer lineages are MRPL18, LSP1P1, and CENPU. Each is linked with SLC10A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A6-to-partner and partner-to-SLC10A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPL18 grouped by SLC10A6-low versus SLC10A6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A6→partner) and Y-score (partner→SLC10A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL18 →	+0.468	+3.711	<.001	<.001	3	2
UCEC	LSP1P1 →	+0.302	+2.213	<.001	.001	3	2
UCEC	CENPU →	+0.922	+2.695	<.001	<.001	3	2
UCEC	C1orf50 →	+0.271	+3.491	.007	.002	3	2
UCEC	AKIP1 →	+0.433	+2.662	.001	<.001	3	2
UCEC	SEC11C →	+0.586	+3.724	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,085 associations by consensus.

MRPL18 by SLC10A6 expression — UCEC

Explore this box plot interactively →