SLC10A6

Across TCGA pan-cancer cohorts, SLC10A6 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of SLC10A6’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLC10A6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC10A6 is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.

KIRC, LIHC, and BRCA are the cancer types where SLC10A6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC10A6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+1.565	<.001	11	view →
LIHC	All	II,III,IV	+0.277	<.001	7	view →
BRCA	All	III,IV	−1.495	<.001	6	view →
UCEC	All	All	−0.833	<.001	6	view →
THCA	Female	All	−0.482	<.001	5	view →
LUSC	Male	All	+1.128	<.001	4	view →
KICH	All	III,IV	−0.451	.009	3	view →
HNSC	Female	III,IV	+1.308	.022	2	view →
LUAD	All	All	−0.193	.009	2	view →
CHOL	All	All	+0.388	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

SLC10A6–KIRC

Open the KIRC breakdown →