SLC10A6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC10A6 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC10A6-associated genes across cancer lineages are SSX7, TAAR8, and OR9G4. Each is linked with SLC10A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A6-to-partner and partner-to-SLC10A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSX7 grouped by SLC10A6-low versus SLC10A6-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A6→partner) and Y-score (partner→SLC10A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHSSX7 →+0.325+4.285<.001.00731
LUNG_NSCLC_LUADTAAR8 →+0.022+5.662<.001.00231
LUNG_NSCLC_LUADOR9G4 →+0.039+4.887<.001.00931
BLOOD_LymphomaS100G →+0.096+4.867<.001.00931
BLOOD_LymphomaC10orf53 →+0.021+4.867.001.00931
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

SSX7 by SLC10A6 expression — STOMACH

Box plot of SSX7 in SLC10A6-low vs SLC10A6-high samples in STOMACH.

Explore this box plot interactively →

Exploration