SLC10A3

Across TCGA patient cohorts, SLC10A3 mutation is significantly associated with the RNA expression of many other genes, with 2,591 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC10A3-associated genes across cancer lineages are LINC00690, LINC02162, and ELOCP32. Each is linked with SLC10A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A3-to-partner and partner-to-SLC10A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00690 grouped by SLC10A3-low versus SLC10A3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A3→partner) and Y-score (partner→SLC10A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC00690 →	+0.057	+5.418	<.001	.005	3	2
CESC	LINC02162 →	+0.132	+6.144	<.001	.001	3	2
CESC	ELOCP32 →	+0.147	+5.010	<.001	.009	3	2
BLCA	RPS3AP1 →	+0.101	+5.018	<.001	.004	3	2
SKCM	RPL26P34 →	+0.047	+3.292	<.001	.006	3	2
BLCA	HMGB1P50 →	+0.124	+4.463	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,591 associations by consensus.

LINC00690 by SLC10A3 expression — CESC

Explore this box plot interactively →