SLC10A3

Across TCGA cell cohorts, SLC10A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,224 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC10A3-associated GO terms across cancer lineages are Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, Bone cell development, and Osteoclast development. Each is linked with SLC10A3 in more than 16 cancer types. Because this analysis shows association rather than direction, both SLC10A3-to-partner and partner-to-SLC10A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway grouped by SLC10A3-low versus SLC10A3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A3→partner) and Y-score (partner→SLC10A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.239	+1.553	<.001	<.001	3	17
LARGE_INTESTINE	Bone cell development →	+0.216	+0.949	<.001	<.001	3	14
LARGE_INTESTINE	Osteoclast development →	+0.216	+0.949	<.001	<.001	3	14
BONE	Viral protein processing →	+0.126	+1.287	<.001	<.001	3	13
BONE	Negative regulation of response to endoplasmic reticulum stress →	+0.168	+1.555	<.001	<.001	3	12
BONE	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.222	+1.738	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,224 associations by consensus.

Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway by SLC10A3 expression — BONE

Explore this box plot interactively →