SLC10A3

Across TCGA cell cohorts, SLC10A3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC10A3-associated genes across cancer lineages are SCGB3A2, WFDC11, and FABP12. Each is linked with SLC10A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A3-to-partner and partner-to-SLC10A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB3A2 grouped by SLC10A3-low versus SLC10A3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A3→partner) and Y-score (partner→SLC10A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SCGB3A2 →	+0.117	+4.922	<.001	.009	3	1
BLOOD_Leukemia	WFDC11 →	+0.041	+5.539	<.001	.003	3	1
BLOOD_Leukemia	FABP12 →	+0.085	+5.201	<.001	.006	3	1
BLOOD_Leukemia	GALP →	+0.058	+5.201	<.001	.006	3	1
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
LARGE_INTESTINE	RSC1A1 →	+0.911	+3.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

SCGB3A2 by SLC10A3 expression — BLOOD_Leukemia

Explore this box plot interactively →