SLBP

Across TCGA patient cohorts, SLBP protein abundance is significantly associated with the RNA expression of many other genes, with 13,488 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLBP-associated genes across cancer lineages are NSD2, NCAPH, and KIF23. Each is linked with SLBP in more than 8 cancer types. Because this analysis shows association rather than direction, both SLBP-to-partner and partner-to-SLBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLBP versus NSD2 in OV, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLBP→partner) and Y-score (partner→SLBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NSD2 →	+0.808	+0.408	.001	.004	2	9
UCEC	NCAPH →	+0.816	+0.514	<.001	<.001	3	8
GBM	KIF23 →	+1.154	+0.506	<.001	<.001	3	8
GBM	KNL1 →	+1.224	+0.492	<.001	<.001	3	8
COAD	TACC3 →	+1.193	+0.816	<.001	<.001	3	8
GBM	ZGRF1 →	+0.689	+0.375	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,488 associations by consensus.

SLBP vs NSD2 — OV

Explore this scatter interactively →