SLBP

Across TCGA cell cohorts, SLBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,211 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLBP-associated GO terms across cancer lineages are Positive regulation of chromosome condensation, Regulation of mitotic sister chromatid separation, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with SLBP in more than 19 cancer types. Because this analysis shows association rather than direction, both SLBP-to-partner and partner-to-SLBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome condensation grouped by SLBP-low versus SLBP-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLBP→partner) and Y-score (partner→SLBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of chromosome condensation →	+0.261	+0.647	<.001	.001	3	20
KIDNEY	Regulation of mitotic sister chromatid separation →	+0.166	+0.727	.001	.001	3	17
KIDNEY	Regulation of metaphase/anaphase transition of cell cycle →	+0.109	+0.730	<.001	<.001	3	17
KIDNEY	Positive regulation of chromosome separation →	+0.187	+0.753	<.001	.001	3	17
SKIN	Regulation of mitotic metaphase/anaphase transition →	+0.111	+0.832	<.001	<.001	3	17
KIDNEY	Regulation of mitotic sister chromatid segregation →	+0.157	+0.516	.001	.008	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,211 associations by consensus.

Positive regulation of chromosome condensation by SLBP expression — OESOPHAGUS

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